Erectile dysfunction is a sexual problem that is common to men at any age. The penis of a person who is affected with erectile dysfunction is feeble and limp. It loses its ability to be erect as rigid as rock.
Inadequate blood flow:
An erection is stimulated when there is activation in the nervous system or stimulation in the brain due to some external factors like sound, smell, vision, dreams, thoughts etc. In this case, the blood flow to the penis increases. The vascular muscle in the spongy area of corpora cavernosa fills up with blood and outflow of the blood is cut off to maintain an erection. A limp erection or a failed erection is attributed when the blood supply to the penis is insufficient.
There are network of nerve cells known as alpha- 2 adrenergic which limits the amount of blood entering the penis. During the time of erection the action of alpha-2 adrenergic is stopped, thus blood flows into the penis. Even after a signal from the brain if there is not much blood flow to the penis then the erection subsidizes or there is weak erection or no erection at all.
Nitric oxide Deficiency:
The erection is triggered by blood flow to penis. Nitric oxide plays the role of pressurizing the blood to sustain an erection.
When the brain gets aroused, it sends a signal to the penis. Nerve cells in the penis' corpora cavernosa start producing nitric oxide, which leads to the creation of cGMP. The cGMP causes arteries in the corpora cavernosa to dilate, causing lots of blood to flow into the penis. Thus an erection occurs.
When men suffer from erectile dysfunction the nerves in the penis produces Nitric Oxide but the amount of cGMP created is very less to sustain a firm erection.
Irregular neurological function
The decrease in neural and autonomic functioning also leads to erectile dysfunction. There are neurotransmitters in the brain which sets series of responses in brain that make an erection possible.
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